HPLC Column, RP C4 Butyl, 5um, 4.6mm ID x 150mm Length, 100A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C4™ is a reversed-phase HPLC stationary phase designed for the separation of hydrophobic and neutral compounds where less retention is desired than with traditional C8 or C18 phases. Manufactured using a four-carbon butyl ligand bonded to ultra-high purity silica and fully double end capped, this stationary phase provides reproducible chromatographic performance and is widely used as an alternative in USP methods requiring L26 chemistry. Its reduced hydrophobicity compared to longer-chain bonded phases makes it particularly useful for rapid analyses, routine testing, and method development.
68504-15P is an HPLC column packed with 5 µm RP C4™ particles featuring a 100 Å pore size in a 4.6 mm ID x 150 mm format. The 150 mm length provides increased chromatographic resolution and peak capacity compared to shorter column configurations, while the 5 µm particles allow operation at higher flow rates with lower backpressure than smaller particle columns. Typical operating flow rates are approximately 1.0–2.0 mL/min depending on mobile phase composition, temperature, and system configuration.
This column is commonly used for hydrophobic and neutral compounds in reversed-phase HPLC when reduced retention is desirable. Compared to C8 phases, RP C4™ typically provides lower retention, making it useful for compounds that may otherwise be excessively retained on more hydrophobic stationary phases. The 150 mm format offers enhanced resolving power for challenging separations and is one of the most popular RP C4™ column configurations for routine laboratory use.
Key Benefits
RP C4™ stationary phase
USP L26 equivalent chemistry
Butyl bonded phase
Fully double end capped
Ultra-high purity silica support
Less retention than C8 phases
Suitable for rapid analyses
Lower backpressure than smaller particle columns
5 µm particle size
One of the most popular RP C4™ column configurations
Typical Applications
USP L26 methods
Method development
Method scouting
Hydrophobic compound analysis
Neutral compound analysis
Reversed-phase HPLC
Pharmaceutical analysis
Quality control testing
Research and development
Routine analytical testing
Specifications
Product Type: HPLC Column
Stationary Phase: RP C4™
USP Classification: L26
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double End Capped
Particle Size: 5 µm
Pore Size: 100 Å
Column Dimensions: 4.6 mm ID x 150 mm
Length: 150 mm
Typical Flow Rate: 1.0–2.0 mL/min
Brand: Cogent
Important Notes
Designed for hydrophobic and neutral compounds
Provides less retention than C8 stationary phases
Suitable for rapid reversed-phase separations
The 150 mm length provides greater resolution and peak capacity than shorter column formats
5 µm particles allow higher flow rates with lower backpressure
Fully double end capped to minimize secondary interactions
Frequently used for method development and scouting studies
Excellent alternative for USP L26 methods
One of the most popular Cogent RP C4™ column formats